Many varieties of bitter orange are used for their essential oil, and are found in perfume, used as a flavoring or as a solvent, and also for consumption.
The bitter orange flower oil is commonly known as neroli oil and possesses several therapeutic properties. Evidence shows that it has anti-anxiety, anticancer, anti-obesity, antioxidant, antibacterial, antidiabetic, and pesticidal properties.
Citrus aurantium essential oil aromatherapy reduced anxiety level in the great part of stress conditions studied (subjects affected by chronic myeloid leukemia and preoperative patients) except for a sample of patients subjected to colonoscopy. Exposition to Citrus sinensis essential oil in clinical studies shows to be positive in reducing anxiety level in patients waiting for dental treatment as well as in healthy volunteers submitted to an anxiogenic situation.